Scientific References: Micronutrients and Ageing
Scientific References

Role of specific micronutrients in some of the manifestations of ageing
Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, et al
Nature, 2006 Nov 16;444(7117):337-42. Epub 2006 Nov 1.
[Abstract]

Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate
Dario R. Valenzano1, Eva Terzibasi2, Tyrone Genade2, Antonino Cattaneo3, 4, Luciano Domenici2, 5 and Alessandro Cellerino1, 2
Current Biology, Volume 16, Issue 3, 296-300, 7 February 2006 
doi: 10.1016/j.cub.2005.12.038
[Abstract] [Full Text] [Full Text PDF]

Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Taylor A, Jacques PF, Chylack LT Jr, et al.
Am J Clin Nutr 2002; 75: 540-9.
[Abstract][Full Text][Full Text PDF]

Long-term nutrient intake and early age-related nuclear lens opacities
Jacques PF, Chylack LTJ, Hankinson SE, et al.
Arch Ophthalmol 2001; 119: 1009-19.
[Abstract][Full Text][Full Text PDF]

Age­Related Eye Disease Study Research Group. A randomized, placebo­controlled clinical trial of high dose supplementation with vitamins C and E, beta­carotene and zinc for age­related macular degeneration and vision loss: AREDS report no. 8.
Arch Ophthalmol 2001;119:1417­36.
[Abstract][Full Text]

Flavonoid intake and risk of chronic diseases1,2
Paul Knekt, Jorma Kumpulainen, Ritva Järvinen, Harri Rissanen, Markku Heliövaara, Antti Reunanen, Timo Hakulinen and Arpo Aromaa
American Journal of Clinical Nutrition, Vol. 76, No. 3, 560-568, September 2002
[Abstract][Full Text][Full Text PDF]

The Relation of Serum Levels of Antioxidant Vitamins C and E, Retinol and Carotenoids with Pulmonary Function in the General Population
HOLGER J. SCHÜNEMANN, BRYDON J. B. GRANT, JO L. FREUDENHEIM, PAOLA MUTI, RICHARD W. BROWNE, JULIE A. DRAKE, ROBERT A. KLOCKE, and MAURIZIO TREVISAN;  Am. J. Respir. Crit. Care Med., Volume 163, Number 5, April 2001, 1246-1255
[Abstract][Full Text][Full Text PDF]

A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease; Mary Sano, Ph.D., Christopher Ernesto, M.S., Ronald G. Thomas, Ph.D., Melville R. Klauber, Ph.D., Kimberly Schafer, M.S., Michael Grundman, M.D., M.P.H., Peter Woodbury, John Growdon, M.D., Carl W. Cotman, Ph.D., Eric Pfeiffer, M.D., Lon S. Schneider, M.D., and Leon J. Thal, M.D. for the Members of the Alzheimer's Disease Cooperative Study; N Engl J Med 1997; 336:1216-1222 April 24, 1997
[Abstract][Full Text][Full Text PDF]

The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Maccioni RB, Munoz JP, Barbeito L. Arch Med Res. 2001;32(5):367-381. 
[Abstract]

Dietary intake of fatty acids and fish in relation to cognitive performance at middle age. Kalmijn S, van Boxtel MP, Ocke M, Verschuren WM, Kromhout D, Launer LJ. Neurology. 2004;62(2):275-280. 
[Abstract]

Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Kalmijn S, Launer LJ, Ott A, Witteman JC, Hofman A, Breteler MM. Ann Neurol. 1997;42(5):776-782.
[Abstract]

Fatty acids, lipid metabolism and Alzheimer pathology. Hooijmans CR, Kiliaan AJ. Eur J Pharmacol. 2008;585(1):176-196. 
[Abstract]

DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease. National Institutes of Health. ClinicalTrials.
[Web page].

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Morris MC, Evans DA, Bienias JL, et al. Arch Neurol. 2003;60(7):940-946. 
[Abstract]

Current and future therapy in Alzheimer's disease. van Marum RJ. Fundam Clin Pharmacol. 2008;22(3):265-274.
[Abstract]

Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia. Kyle DJ, Schaefer E, Patton G, Beiser A. Lipids. 1999;34 Suppl:S245.
[Abstract]

Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment. Conquer JA, Tierney MC, Zecevic J, Bettger WJ, Fisher RH. Lipids. 2000;35(12):1305-1312. 
[Abstract]

Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study. Tully AM, Roche HM, Doyle R, et al. Br J Nutr. 2003;89(4):483-489. 
[Abstract]

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Schaefer EJ, Bongard V, Beiser AS, et al. Arch Neurol. 2006;63(11):1545-1550. 
[Abstract]